{"id":5606,"date":"2024-12-12T14:30:44","date_gmt":"2024-12-12T13:30:44","guid":{"rendered":"https:\/\/www.benarroche-urologie.fr\/lapeyronies-disease\/"},"modified":"2026-01-06T12:44:23","modified_gmt":"2026-01-06T11:44:23","slug":"lapeyronies-disease","status":"publish","type":"page","link":"https:\/\/www.benarroche-urologie.fr\/en\/your-needs\/lapeyronies-disease\/","title":{"rendered":"Lapeyronie’s disease"},"content":{"rendered":"\t\t
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Lapeyronie's disease<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tHome \/ <\/a>Lapeyronie’s disease\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Peyronie's Disease: Understanding and Treating Effectively<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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What is Peyronie's disease?<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Peyronie’s disease corresponds to the formation of localized fibrosis<\/strong> (plaque) at the level of the tunica albuginea, the membrane that surrounds the corpora cavernosa of the penis.<\/p>

This fibrosis causes deformation and<\/strong> curvature of the erect penis<\/strong> , sometimes accompanied by pain and decreased rigidity.
Although benign, this condition can have a major impact on sexuality and self-confidence<\/strong> .<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Natural course of the disease<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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It usually evolves in two phases<\/strong> :<\/p>

Acute, inflammatory phase (not systematically observed)<\/strong> : pain during erection, appearance and possible worsening of deformity and curvature.<\/p>

Stable, chronic phase<\/strong> : disappearance of pain, but persistence of the deformity.
Without appropriate treatment, the disease most often stabilizes with a permanent curvature<\/strong> , sometimes causing discomfort during intercourse.<\/p>

The initial treatment aims to stabilize, soften and straighten<\/strong> the penis in order to limit the need for surgery.<\/b><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Conservative treatment: a biological and mechanical approach<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Conservative treatment refers to all non-surgical solutions offered to treat Peyronie’s disease. The objective is twofold: to halt the progression of the disease<\/b> (inflammatory phase) and to attempt to reverse the curvature<\/b> without resorting to surgery. This modern approach relies on a powerful synergy: the biological action of PRP<\/b> combined with the mechanical action of traction<\/b> . <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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1. PRP (Platelet Rich Plasma) injections<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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PRP is an innovative technique derived from regenerative medicine. It uses your body’s own natural healing abilities to repair damaged tissue. <\/p>

How does it work?<\/b> The procedure is simple and takes place in the doctor’s office: after a standard blood test, the blood is centrifuged to isolate the ultra-concentrated platelet plasma. This concentrate is then reinjected directly into the area of the Peyronie’s plaque. <\/p>

The growth factors<\/strong> contained in PRP stimulate:<\/p>

\u2705 Stimulate cell regeneration<\/b> and the appearance of new blood vessels (neo-vascularization).<\/p>

\u2705 Promote the gradual resorption<\/b> of fibrosis (the rigid scar).<\/strong><\/p>

\u2705 Restore the elasticity<\/b> of erectile tissues to allow for better penis extension.<\/p>

The advantages of PRP:<\/b> It is a 100% natural and autologous<\/b> treatment (derived from your own body), which eliminates any risk of rejection or allergy. The standard protocol generally requires several spaced-out sessions to achieve optimal results.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Focus on a new injectable treatment: PEROVIAL (Hyaluronic Acid)<\/h3>

PEROVIAL<\/b> (IBSA Laboratory) represents a new non-surgical therapeutic option in the management of Peyronie’s disease. This is an injectable solution based on hyaluronic acid<\/b> , a molecule naturally present in the body, known for its hydrating and viscoelastic properties.<\/p>

How does it work?<\/b> PEROVIAL is administered directly into the heart of the fibrous plaque (intralesional injection). Its action is twofold: <\/p>

  1. Tissue restructuring:<\/b> Hyaluronic acid will infiltrate the fibrositis to hydrate it deeply. This helps to space out the inflammatory cells and reduce the density of the plaque. <\/p><\/li>

  2. Softening:<\/b> By recreating a more flexible physiological environment, the injection aims to reduce the rigidity of the pathological area, thus relieving pain in the active phase.<\/p><\/li><\/ol>

    To maximize results, it is often recommended to combine these injections with mechanical therapy.<\/b> The injection “prepares” the tissue by softening it, making stretching exercises more effective in correcting the curvature.<\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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    2. Mechanical traction (vacuum or penile traction device)<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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    Why stretch fabrics?<\/p>

    Peyronie’s disease is characterized by the formation of a fibrous, inelastic plaque which, by contracting, leads to curvature and loss of length of the penis.<\/p>

    The principle of conservative treatment is to counteract this retraction<\/b> . By applying a controlled mechanical force to the tissues, we stimulate the natural ability of cells to regenerate and reorganize themselves. The goal is therefore to transform a mechanical stimulus (stretching) into a biological healing response.<\/p>

    Penile extender devices (traction) or the Vacuum (vacuum pump) allow for gentle, progressive and daily stretching<\/b> of the penis.<\/p>

    Unlike surgery, which acts in a single procedure, this technique relies on consistency. Continuous stretching will: <\/p>

    1. To soften<\/b> the fibrotic plaque (the internal scar).<\/p><\/li>

    2. Stimulate<\/b> the remodeling of healthy tissues.<\/p><\/li>

    3. Actively fight<\/b> against the natural retraction of the disease.<\/p><\/li><\/ol>

      The key to success with traction therapy is perseverance<\/b> . The results are not immediate, but take place over several months. It is a fundamental treatment that requires discipline, but is essential to prepare the tissues and optimize the result, whether to avoid surgery or to prepare for it.<\/p>

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      Expected results and benefits of conservative treatment<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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      The combination of injection and mechanical traction<\/strong> is currently the first-line approach<\/strong> in Peyronie’s disease.
      When started early and followed regularly, it yields very encouraging results<\/strong> :<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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      \n\t\t\t\t\t\tImprovement of curvature in 70 to 80% of cases\n (often a 30-50% reduction in the deflection angle)\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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      \n\t\t\t\t\t\tPreservation of penis length and symmetry\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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      \n\t\t\t\t\t\tImprovement of erectile function\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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      \n\t\t\t\t\t\tImproved comfort during sexual intercourse\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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      \n\t\t\t\t\t\tReduction or disappearance of pain in the inflammatory phase\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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      \n\t\t\t\t\t\tBetter overall satisfaction during intercourse \t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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      \ud83d\udca1 Thanks to this therapeutic strategy, the vast majority of patients avoid surgery<\/b> and regain a much more satisfying sex life.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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      The surgical option<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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      Although often reserved for cases where medical treatment has failed, surgery may be considered from the outset if the deformity is severe or if the patient desires it. The goal is to correct the curvature using appropriate techniques. However, it is essential to carefully assess the benefit-risk balance (penile shortening, risk of erectile dysfunction) before proceeding. <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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      Do you suspect Peyronie's disease?<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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      \n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tConsultation appointment<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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      Requirements<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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